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Synaptic Vesicles in Mature Calyx of Held Synapses Sense Higher Nanodomain Calcium Concentrations during Action Potential-Evoked Glutamate Release

During development of the calyx of Held synapse, presynaptic action potentials (APs) become substantially faster and briefer. Nevertheless, this synapse is able to upregulate quantal output triggered by arriving APs. Briefer APs lead to less effective gating of voltage-gated Ca(2+) channels (VGCCs)....

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Wang, Lu-Yang, Neher, Erwin, Taschenberger, Holger
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671236/
https://ncbi.nlm.nih.gov/pubmed/19118179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4245-08.2008
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