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Synaptic Vesicles in Mature Calyx of Held Synapses Sense Higher Nanodomain Calcium Concentrations during Action Potential-Evoked Glutamate Release

During development of the calyx of Held synapse, presynaptic action potentials (APs) become substantially faster and briefer. Nevertheless, this synapse is able to upregulate quantal output triggered by arriving APs. Briefer APs lead to less effective gating of voltage-gated Ca(2+) channels (VGCCs)....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Wang, Lu-Yang, Neher, Erwin, Taschenberger, Holger
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671236/
https://ncbi.nlm.nih.gov/pubmed/19118179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4245-08.2008
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