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Preferential potentiation of fast-releasing synaptic vesicles by cAMP at the calyx of Held

We have studied the effects of cAMP on synaptic transmission at the calyx of Held and found that forskolin (an activator of adenylate cyclase) and 8-Br-cAMP (a membrane-permeable analog of cAMP) potentiated excitatory postsynaptic currents (EPSCs). Direct sampling of miniature EPSCs (mEPSCs) and non...

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Bibliographic Details
Main Authors: Sakaba, Takeshi, Neher, Erwin
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC14590/
https://ncbi.nlm.nih.gov/pubmed/11134533
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