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New N-phenyl-4,5-dibromopyrrolamides as DNA gyrase B inhibitors

Due to the rapid development of antimicrobial resistance, the discovery of new antibacterials is essential in the fight against potentially lethal infections. The DNA gyrase B (GyrB) subunit of bacterial DNA gyrase is an excellent target for the design of antibacterials, as it has been clinically va...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Medchemcomm
Hauptverfasser: Zidar, Nace, Macut, Helena, Tomašič, Tihomir, Peterlin Mašič, Lucija, Ilaš, Janez, Zega, Anamarija, Tammela, Päivi, Kikelj, Danijel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596384/
https://ncbi.nlm.nih.gov/pubmed/31303999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00224c
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