Transynaptic Action of Botulinum Neurotoxin Type A at Central Cholinergic Boutons

Botulinum neurotoxin Type A (BoNT/A) is an effective treatment for several movement disorders, including spasticity and dystonia. BoNT/A acts by cleaving synaptosomal-associated protein of 25 kDa (SNAP-25) at the neuromuscular junction, thus blocking synaptic transmission and weakening overactive mu...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Caleo, Matteo, Spinelli, Matteo, Colosimo, Francesca, Matak, Ivica, Rossetto, Ornella, Lackovic, Zdravko, Restani, Laura
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2018
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596210/
https://ncbi.nlm.nih.gov/pubmed/30315128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0294-18.2018
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