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Evidence for Anterograde Transport and Transcytosis of Botulinum Neurotoxin A (BoNT/A)

Botulinum neurotoxin type A (BoNT/A) is a metalloprotease that blocks synaptic transmission via the cleavage of SNAP-25 (synaptosomal-associated protein of 25 kDa). BoNT/A is successfully used in clinical neurology for the treatment of several neuromuscular pathologies and pain syndromes. Despite it...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Restani, Laura, Antonucci, Flavia, Gianfranceschi, Laura, Rossi, Chiara, Rossetto, Ornella, Caleo, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623022/
https://ncbi.nlm.nih.gov/pubmed/22049408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2618-11.2011
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