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Botulinum Neurotoxins A and E Undergo Retrograde Axonal Transport in Primary Motor Neurons

The striking differences between the clinical symptoms of tetanus and botulism have been ascribed to the different fate of the parental neurotoxins once internalised in motor neurons. Tetanus toxin (TeNT) is known to undergo transcytosis into inhibitory interneurons and block the release of inhibito...

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Detalhes bibliográficos
Main Authors: Restani, Laura, Giribaldi, Francesco, Manich, Maria, Bercsenyi, Kinga, Menendez, Guillermo, Rossetto, Ornella, Caleo, Matteo, Schiavo, Giampietro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531519/
https://ncbi.nlm.nih.gov/pubmed/23300443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003087
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