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Central Action of Peripherally Applied Botulinum Toxin Type A on Pain and Dural Protein Extravasation in Rat Model of Trigeminal Neuropathy

BACKGROUND: Infraorbital nerve constriction (IoNC) is an experimental model of trigeminal neuropathy. We investigated if IoNC is accompanied by dural extravasation and if botulinum toxin type A (BoNT/A) can reduce pain and dural extravasation in this model. METHODOLOGY/PRINCIPAL FINDINGS: Rats which...

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Detalhes bibliográficos
Main Authors: Filipović, Boris, Matak, Ivica, Bach-Rojecky, Lidija, Lacković, Zdravko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251614/
https://ncbi.nlm.nih.gov/pubmed/22238656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029803
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