Impaired Mitochondrial Fatty Acid Synthesis Leads to Neurodegeneration in Mice

There has been a growing interest toward mitochondrial fatty acid synthesis (mtFAS) since the recent discovery of a neurodegenerative human disorder termed MEPAN (mitochondrial enoyl reductase protein associated neurodegeneration), which is caused by mutations in the mitochondrial enoyl-CoA/ACP (acy...

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Pubblicato in:J Neurosci
Autori principali: Nair, Remya R., Koivisto, Henna, Jokivarsi, Kimmo, Miinalainen, Ilkka J., Autio, Kaija J., Manninen, Aki, Poutiainen, Pekka, Tanila, Heikki, Hiltunen, J. Kalervo, Kastaniotis, Alexander J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2018
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595986/
https://ncbi.nlm.nih.gov/pubmed/30266742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3514-17.2018
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