Defects in Mitochondrial Fatty Acid Synthesis Result in Failure of Multiple Aspects of Mitochondrial Biogenesis in Saccharomyces cerevisiae

Mitochondrial fatty acid synthesis (mtFAS) shares acetyl-CoA with the Krebs cycle as a common substrate and is required for the production of octanoic acid (C8) precursors of lipoic acid (LA) in mitochondria. MtFAS is a conserved pathway essential for respiration. In a genetic screen in Saccharomyce...

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Main Authors: Kursu, V. A. Samuli, Pietikäinen, Laura P., Fontanesi, Flavia, Aaltonen, Mari J., Suomi, Fumi, Nair, Remya Raghavan, Schonauer, Melissa S., Dieckmann, Carol L., Barrientos, Antoni, Hiltunen, J. Kalervo, Kastaniotis, Alexander J.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153884/
https://ncbi.nlm.nih.gov/pubmed/24102902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12402
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