Pathway genes and metabolites in thiopurine therapy in Korean children with acute lymphoblastic leukaemia

AIMS: We aimed to investigate the impact of various genetic polymorphisms affecting thiopurine metabolism pathways and toxicity in paediatric acute lymphoblastic leukaemia patients for the first time in Korea. METHODS: From May 2006 to September 2016, 139 paediatric acute lymphoblastic leukaemia pat...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Choi, Rihwa, Sohn, Insuk, Kim, Min‐Ji, Woo, Hye In, Lee, Ji Won, Ma, Youngeun, Yi, Eun Sang, Koo, Hong Hoe, Lee, Soo‐Youn
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595296/
https://ncbi.nlm.nih.gov/pubmed/30927276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13943
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