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Monitoring Thiopurine Metabolites in Korean Pediatric Patients with Inflammatory Bowel Disease

PURPOSE: This study aimed to assess the role of thiopurine S-methyltransferase (TPMT) and 6-thioguanine nucleotide (6-TGN) as predictors of clinical response and side effects to azathioprine (AZA), and estimate the optimal AZA dose in Korean pediatric inflammatory bowel disease (IBD) patients. MATER...

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Autori principali: Kim, Mi Jin, Lee, Soo Youn, Choe, Yon Ho
Natura: Artigo
Lingua:Inglês
Pubblicazione: Yonsei University College of Medicine 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108814/
https://ncbi.nlm.nih.gov/pubmed/25048487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2014.55.5.1289
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