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Association of variants of prodynorphin promoter 68-bp repeats in Caucasians with opioid dependence diagnosis: Effect on age trajectory of heroin use
The dynorphin/kappa opioid receptor (Dyn/KOR) system is involved in reward processing and dysphoria/anhedonia. Exposure to mu-opioid receptor agonists such as heroin increases expression of the prodynorphin gene (PDYN) in the brain. In this study in a Caucasian cohort, we examined the association of...
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| Veröffentlicht in: | Neurosci Lett |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6594859/ https://ncbi.nlm.nih.gov/pubmed/30936032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2019.03.038 |
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