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Dopamine gene variants in opioid addiction: comparison of dependent patients, nondependent users and healthy controls

AIM: To determine whether specific dopaminergic system gene variants are associated with opioid dependence. PATIENTS & METHODS: Subjects included 153 healthy controls, 163 opioid exposed, but not dependent and 281 opioid dependent. Genotypes of 90 variants in 13 genes were examined. RESULTS: The...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics
Main Authors: Randesi, Matthew, van den Brink, Wim, Levran, Orna, Yuferov, Vadim, Blanken, Peter, van Ree, Jan M, Ott, Jurg, Kreek, Mary Jeanne
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826863/
https://ncbi.nlm.nih.gov/pubmed/29210332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2017-0134
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