GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients

GPIHBP1, a GPI-anchored protein of capillary endothelial cells, binds lipoprotein lipase (LPL) within the subendothelial spaces and shuttles it to the capillary lumen. GPIHBP1-bound LPL is essential for the margination of triglyceride-rich lipoproteins (TRLs) along capillaries, allowing the lipolyti...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Hu, Xuchen, Matsumoto, Ken, Jung, Rachel S, Weston, Thomas A, Heizer, Patrick J, He, Cuiwen, Sandoval, Norma P, Allan, Christopher M, Tu, Yiping, Vinters, Harry V, Liau, Linda M, Ellison, Rochelle M, Morales, Jazmin E, Baufeld, Lynn J, Bayley, Nicholas A, He, Liqun, Betsholtz, Christer, Beigneux, Anne P, Nathanson, David A, Gerhardt, Holger, Young, Stephen G, Fong, Loren G, Jiang, Haibo
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2019
Matèries:
Biochemistry and Chemical Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594755/
https://ncbi.nlm.nih.gov/pubmed/31169500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47178
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