Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery

G3BP-1 and -2 (hereafter referred to as G3BP) are multifunctional RNA-binding proteins involved in stress granule (SG) assembly. Viruses from diverse families target G3BP for recruitment to replication or transcription complexes in order to block SG assembly but also to acquire pro-viral effects via...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Götte, Benjamin, Panas, Marc D., Hellström, Kirsi, Liu, Lifeng, Samreen, Baila, Larsson, Ola, Ahola, Tero, McInerney, Gerald M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594655/
https://ncbi.nlm.nih.gov/pubmed/31199850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007842
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