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The C-Terminal Repeat Domains of nsP3 from the Old World Alphaviruses Bind Directly to G3BP

The Old World alphaviruses block stress granule assembly by sequestration of RasGAP SH3-domain binding protein (G3BP). Here, we show that the proline-rich sequences in the hypervariable domain of nonstructural protein 3 (nsP3) of both Semliki Forest virus and Chikungunya virus were dispensable for b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Panas, Marc D., Ahola, Tero, McInerney, Gerald M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019107/
https://ncbi.nlm.nih.gov/pubmed/24623412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00439-14
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