Profiling interactions of vaborbactam with metallo-β-lactamases

β-Lactams are the most successful antibacterials, yet their use is threatened by resistance, importantly as caused by β-lactamases. β-Lactamases fall into two mechanistic groups: the serine β-lactamases that utilise a covalent acyl-enzyme mechanism and the metallo β-lactamases that utilise a zinc-bo...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Bioorg Med Chem Lett
Main Authors: Langley, Gareth W., Cain, Ricky, Tyrrell, Jonathan M., Hinchliffe, Philip, Calvopiña, Karina, Tooke, Catherine L., Widlake, Emma, Dowson, Christopher G., Spencer, James, Walsh, Timothy R., Schofield, Christopher J., Brem, Jürgen
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Science Ltd 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593178/
https://ncbi.nlm.nih.gov/pubmed/31171422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.05.031
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki