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smFRET Probing Reveals Substrate-Dependent Conformational Dynamics of E. coli Multidrug MdfA

Bacterial multidrug-resistance transporters of the major facilitator superfamily are distinguished by their extraordinary ability to bind structurally diverse substrates, thus serving as a highly efficient tool to protect cells from multiple toxic substances present in their environment, including a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Zhu, Yongping, He, Lingli, Liu, Yue, Zhao, Yongfang, Zhang, Xuejun C.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592872/
https://ncbi.nlm.nih.gov/pubmed/31146923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.04.034
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