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Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition
MdfA is a prototypical H(+)-coupled multidrug transporter that is characterized by extraordinarily broad substrate specificity. The involvement of specific H-bonds in MdfA-drug interactions and the simplicity of altering the substrate specificity of MdfA contradict the promiscuous nature of multidru...
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| Publicado no: | Commun Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6572762/ https://ncbi.nlm.nih.gov/pubmed/31240248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0446-y |
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