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Enamide Prodrugs of Acetyl Phosphonate Deoxy-d-xylulose-5-phosphate Synthase Inhibitors as Potent Antibacterial Agents

To fight the growing threat of antibiotic resistance, new antibiotics are required that target essential bacterial processes other than protein, DNA/RNA, and cell wall synthesis which constitute the majority of currently used antibiotics. 1-Deoxy-d-xylulose-5-phosphate (DXP) synthase is a vital enzy...

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Detaylı Bibliyografya
Yayımlandı:ACS Infect Dis
Asıl Yazarlar: Bartee, David, Sanders, Sara, Phillips, Paul D., Harrison, Mackenzie J., Koppisch, Andrew T., Meyers, Caren L. Freel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592275/
https://ncbi.nlm.nih.gov/pubmed/30614674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00307
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