Revealing Substrate Promiscuity of 1-Deoxy-D-Xylulose 5-Phosphate Synthase

Eitemau Tebyg

• 1-Deoxy-d-xylulose 5-Phosphate Synthase Catalyzes a Novel Random Sequential Mechanism
  gan: Brammer, Leighanne A., et al.
  Cyhoeddwyd: (2011)
• Targeting the Unique Mechanism of Bacterial 1-deoxy-D-xylulose 5-phosphate (DXP) Synthase
  gan: Bartee, David, et al.
  Cyhoeddwyd: (2018)
• Selective inhibition of E. coli 1-deoxy-D-xylulose-5-phosphate synthase by acetylphosphonates()
  gan: Smith, Jessica M., et al.
  Cyhoeddwyd: (2011)
• Defining critical residues for substrate binding to 1-deoxy-d-xylulose 5-phosphate synthase: Active site substitutions stabilize the pre-decarboxylation intermediate C2α-lactylthiamin diphosphate
  gan: Basta, Leighanne A. Brammer, et al.
  Cyhoeddwyd: (2014)
• Observation of thiamin-bound intermediates and microscopic rate constants for their interconversion on 1-deoxy-D-xylulose 5-phosphate synthase: 600-fold rate acceleration of pyruvate decarboxylation by D-glyceraldehyde-3-phosphate
  gan: Patel, Hetalben, et al.
  Cyhoeddwyd: (2012)