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Revealing Substrate Promiscuity of 1-Deoxy-D-Xylulose 5-Phosphate Synthase

[Image: see text] A study of DXP synthase has revealed flexibility in the acceptor substrate binding pocket for non-polar substrates, and has uncovered new details of the catalytic mechanism to show that pyruvate can act as both donor and acceptor substrate.

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Detalhes bibliográficos
Main Authors: Brammer, Leighanne A., Meyers, Caren Freel
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761658/
https://ncbi.nlm.nih.gov/pubmed/19778006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol901961q
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