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1-Deoxy-d-xylulose 5-Phosphate Synthase Catalyzes a Novel Random Sequential Mechanism

Emerging resistance of human pathogens to anti-infective agents make it necessary to develop new agents to treat infection. The methylerythritol phosphate pathway has been identified as an anti-infective target, as this essential isoprenoid biosynthetic pathway is widespread in human pathogens but a...

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Detalhes bibliográficos
Main Authors: Brammer, Leighanne A., Smith, Jessica M., Wade, Herschel, Meyers, Caren Freel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196101/
https://ncbi.nlm.nih.gov/pubmed/21878632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259747
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