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Toward Understanding the Chemistry and Biology of 1-Deoxy-d-xylulose 5-phosphate (DXP) Synthase: A Unique Antimicrobial Target at the Heart of Bacterial Metabolism

Antibiotics are the cornerstone of modern healthcare. The 20(th) century discovery of sulfonamides and β-lactam antibiotics altered human society immensely. Simple bacterial infections were no longer a leading cause of morbidity and mortality, and antibiotic prophylaxis greatly reduced the risk of i...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Acc Chem Res
Prif Awduron: Bartee, David, Freel Meyers, Caren L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309272/
https://ncbi.nlm.nih.gov/pubmed/30203647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.8b00321
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