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Sex Differences in Rotenone Sensitivity Reflect the Male-to-Female Ratio in Human Parkinson’s Disease Incidence
There is a critical need to include female subjects in disease research; however, in Parkinson’s disease, where the male-to-female incidence is about 1.5-to-1, the majority of preclinical research is conducted in male animals. The mitochondrial complex I inhibitor, rotenone, is selectively toxic to...
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| Publicado en: | Toxicol Sci |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6592185/ https://ncbi.nlm.nih.gov/pubmed/30907971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz082 |
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