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Astrocyte-specific DJ-1 overexpression protects against rotenone-induced neurotoxicity in a rat model of Parkinson’s disease

DJ-1 is a redox-sensitive protein with several putative functions important in mitochondrial physiology, protein transcription, proteasome regulation, and chaperone activity. High levels of DJ-1 immunoreactivity are reported in astrocytes surrounding pathology associated with idiopathic Parkinson’s...

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Bibliografische gegevens
Gepubliceerd in:Neurobiol Dis
Hoofdauteurs: De Miranda, Briana R., Rocha, Emily M., Bai, Qing, El Ayadi, Amina, Hinkle, David, Burton, Edward A., Greenamyre, J. Timothy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943150/
https://ncbi.nlm.nih.gov/pubmed/29649621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.04.008
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