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DJ-1 expression modulates astrocyte-mediated protection against neuronal oxidative stress
DJ-1 deficiency is a cause of genetic Parkinson’s disease (PARK7 PD). In sporadic PD, however, DJ-1 is abundantly-expressed in reactive astrocytes. This may represent a compensatory protective response. In initial support of this hypothesis, we have shown in vitro that DJ-1 over-expressing astrocyte...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567237/ https://ncbi.nlm.nih.gov/pubmed/23065353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-012-9904-4 |
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