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DJ-1 knock-down in astrocytes impairs astrocyte-mediated neuroprotection against rotenone
Mutations that eliminate DJ-1 expression cause a familial form of Parkinson’s disease (PD). In sporadic PD, and many other neurodegenerative diseases, reactive astrocytes over-express DJ-1 whereas neurons maintain its expression at non-disease levels. Since DJ-1 has neuroprotective properties, and s...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2638760/ https://ncbi.nlm.nih.gov/pubmed/18930142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.09.013 |
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