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Oxidative damage to macromolecules in human Parkinson’s disease and the rotenone model

Parkinson’s disease (PD), the most common neurodegenerative movement disorder, is associated with selective degeneration of nigrostriatal dopamine neurons. While the underlying mechanisms contributing to neurodegeneration in PD appear to be multifactorial, mitochondrial impairment and oxidative stre...

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Detalles Bibliográficos
Autores principales: Sanders, Laurie H., Greenamyre, J. Timothy
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677955/
https://ncbi.nlm.nih.gov/pubmed/23328732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.01.003
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