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Oxidative damage to macromolecules in human Parkinson’s disease and the rotenone model

Parkinson’s disease (PD), the most common neurodegenerative movement disorder, is associated with selective degeneration of nigrostriatal dopamine neurons. While the underlying mechanisms contributing to neurodegeneration in PD appear to be multifactorial, mitochondrial impairment and oxidative stre...

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Autori principali: Sanders, Laurie H., Greenamyre, J. Timothy
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677955/
https://ncbi.nlm.nih.gov/pubmed/23328732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.01.003
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