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Oxidative damage to macromolecules in human Parkinson’s disease and the rotenone model

Parkinson’s disease (PD), the most common neurodegenerative movement disorder, is associated with selective degeneration of nigrostriatal dopamine neurons. While the underlying mechanisms contributing to neurodegeneration in PD appear to be multifactorial, mitochondrial impairment and oxidative stre...

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Bibliografiske detaljer
Main Authors: Sanders, Laurie H., Greenamyre, J. Timothy
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677955/
https://ncbi.nlm.nih.gov/pubmed/23328732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.01.003
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