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Oxidative damage to macromolecules in human Parkinson’s disease and the rotenone model

Parkinson’s disease (PD), the most common neurodegenerative movement disorder, is associated with selective degeneration of nigrostriatal dopamine neurons. While the underlying mechanisms contributing to neurodegeneration in PD appear to be multifactorial, mitochondrial impairment and oxidative stre...

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Detalhes bibliográficos
Main Authors: Sanders, Laurie H., Greenamyre, J. Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677955/
https://ncbi.nlm.nih.gov/pubmed/23328732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.01.003
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