Topological DNA damage, telomere attrition and T cell senescence during chronic viral infections

BACKGROUND: T cells play a key role in controlling viral infections; however, the underlying mechanisms regulating their functions during human viral infections remain incompletely understood. Here, we used CD4 T cells derived from individuals with chronic viral infections or healthy T cells treated...

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Detalhes bibliográficos
Publicado no:Immun Ageing
Main Authors: Ji, Yingjie, Dang, Xindi, Nguyen, Lam Ngoc Thao, Nguyen, Lam Nhat, Zhao, Juan, Cao, Dechao, Khanal, Sushant, Schank, Madison, Wu, Xiao Y., Morrison, Zheng D., Zou, Yue, El Gazzar, Mohamed, Ning, Shunbin, Wang, Ling, Moorman, Jonathan P., Yao, Zhi Q.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591813/
https://ncbi.nlm.nih.gov/pubmed/31285747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-019-0153-z
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