In Vivo Pharmacodynamics of Omadacycline against Staphylococcus aureus in the Neutropenic Murine Thigh Infection Model

Omadacycline is a novel aminomethylcycline antibiotic with potent activity against Staphylococcus aureus, including methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA). We investigated the pharmacodynamic activity of omadacycline against 10 MSSA/MRSA strains in a neut...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Lepak, Alexander J., Zhao, Miao, Marchillo, Karen, VanHecker, Jamie, Andes, David R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591633/
https://ncbi.nlm.nih.gov/pubmed/31036691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00624-19
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