Investigating the properties of TBA variants with twin thrombin binding domains

In this paper, we report studies concerning thrombin binding aptamer (TBA) dimeric derivatives in which the 3′-ends of two TBA sequences have been joined by means of linkers containing adenosine or thymidine residues and/or a glycerol moiety. CD and electrophoretic investigations indicate that all m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Amato, Teresa, Virgilio, Antonella, Pirone, Luciano, Vellecco, Valentina, Bucci, Mariarosaria, Pedone, Emilia, Esposito, Veronica, Galeone, Aldo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591170/
https://ncbi.nlm.nih.gov/pubmed/31235717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45526-z
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