Extracellular and intracellular sphingosine-1-phosphate distinctly regulates exocytosis in chromaffin cells

Sphingosine-1-phosphate (S1P) is an essential bioactive sphingosine lipid involved in many neurological disorders. Sphingosine kinase 1 (SphK1), a key enzyme for S1P production, is concentrated in presynaptic terminals. However, the role of S1P/SphK1 signaling in exocytosis remains elusive. By detec...

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Udgivet i:J Neurochem
Main Authors: Jiang, Zhong-Jiao, Delaney, Taylor L., Zanin, Mark P, Haberberger, Rainer V, Pitson, Stuart M, Huang, Jian, Alford, Simon, Cologna, Stephanie, Keating, Damien J, Gong, Liang-Wei
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591091/
https://ncbi.nlm.nih.gov/pubmed/30963576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14703
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