Structural Basis of an Asymmetric Condensin ATPase Cycle

The condensin protein complex plays a key role in the structural organization of genomes. How the ATPase activity of its SMC subunits drives large-scale changes in chromosome topology has remained unknown. Here we reconstruct, at near-atomic resolution, the sequence of events that take place during...

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Udgivet i:Mol Cell
Main Authors: Hassler, Markus, Shaltiel, Indra A., Kschonsak, Marc, Simon, Bernd, Merkel, Fabian, Thärichen, Lena, Bailey, Henry J., Macošek, Jakub, Bravo, Sol, Metz, Jutta, Hennig, Janosch, Haering, Christian H.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591010/
https://ncbi.nlm.nih.gov/pubmed/31226277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.03.037
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