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Real-time imaging of DNA loop extrusion by condensin

It has been hypothesized that Structural Maintenance of Chromosomes (SMC) protein complexes such as condensin and cohesin spatially organize chromosomes by extruding DNA into large loops. Here, we provide unambiguous evidence for loop extrusion by directly visualizing the formation and processive ex...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Science
Prif Awduron: Ganji, Mahipal, Shaltiel, Indra A., Bisht, Shveta, Kim, Eugene, Kalichava, Ana, Haering, Christian H., Dekker, Cees
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329450/
https://ncbi.nlm.nih.gov/pubmed/29472443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar7831
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