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Real-time imaging of DNA loop extrusion by condensin
It has been hypothesized that Structural Maintenance of Chromosomes (SMC) protein complexes such as condensin and cohesin spatially organize chromosomes by extruding DNA into large loops. Here, we provide unambiguous evidence for loop extrusion by directly visualizing the formation and processive ex...
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| 出版年: | Science |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6329450/ https://ncbi.nlm.nih.gov/pubmed/29472443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar7831 |
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