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Real‐time detection of condensin‐driven DNA compaction reveals a multistep binding mechanism

Condensin, a conserved member of the SMC protein family of ring‐shaped multi‐subunit protein complexes, is essential for structuring and compacting chromosomes. Despite its key role, its molecular mechanism has remained largely unknown. Here, we employ single‐molecule magnetic tweezers to measure, i...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Eeftens, Jorine M, Bisht, Shveta, Kerssemakers, Jacob, Kschonsak, Marc, Haering, Christian H, Dekker, Cees
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709735/
https://ncbi.nlm.nih.gov/pubmed/29118001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797596
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