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Real‐time detection of condensin‐driven DNA compaction reveals a multistep binding mechanism
Condensin, a conserved member of the SMC protein family of ring‐shaped multi‐subunit protein complexes, is essential for structuring and compacting chromosomes. Despite its key role, its molecular mechanism has remained largely unknown. Here, we employ single‐molecule magnetic tweezers to measure, i...
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| Gepubliceerd in: | EMBO J |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5709735/ https://ncbi.nlm.nih.gov/pubmed/29118001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797596 |
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