Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism

Complexes containing a pair of SMC family proteins are fundamental for the 3D organization of genomes in all domains of life. The eukaryotic SMC complexes cohesin and condensin are thought to fold, respectively, interphase and mitotic chromosomes into large loop domains, although the underlying mole...

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書誌詳細
出版年:Nat Struct Mol Biol
主要な著者: Lee, Byung-Gil, Merkel, Fabian, Allegretti, Matteo, Hassler, Markus, Cawood, Christopher, Lecomte, Léa, O’Reilly, Francis J., Sinn, Ludwig R., Gutierrez-Escribano, Pilar, Kschonsak, Marc, Bravo, Sol, Nakane, Takanori, Rappsilber, Juri, Aragon, Luis, Beck, Martin, Löwe, Jan, Haering, Christian H.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610691/
https://ncbi.nlm.nih.gov/pubmed/32661420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0457-x
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