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Expression of drug metabolizing enzymes and transporters in the cochlea: implications for drug delivery and ototoxicity

Inner ear drug delivery is a major area of research and development, but relatively little is known about basic drug metabolism in the cochlea. Additionally, the use of potentially ototoxic drugs such as NSAIDs, chemotherapeutics and aminoglycosides is common, but little is known about the role of m...

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Publicado en:Hear Res
Main Authors: Kennon-McGill, Stefanie, Clemens, Melissa M., McGill, Mitchell R.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590996/
https://ncbi.nlm.nih.gov/pubmed/31121337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2019.05.002
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