HIV-1 Alters Intestinal Expression of Drug Transporters and Metabolic Enzymes: Implications for Antiretroviral Drug Disposition

This study investigated the effects of HIV-1 infection and antiretroviral therapy (ART) on the expression of intestinal drug efflux transporters, i.e., P-glycoprotein (Pgp), multidrug resistance-associated proteins (MRPs), and breast cancer resistance protein (BCRP), and metabolic enzymes, such as c...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: Kis, Olena, Sankaran-Walters, Sumathi, Hoque, M. Tozammel, Walmsley, Sharon L., Dandekar, Satya, Bendayan, Reina
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2016
Ábhair:
Pharmacology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862509/
https://ncbi.nlm.nih.gov/pubmed/26902756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02278-15
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