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Raltegravir Permeability across Blood-Tissue Barriers and the Potential Role of Drug Efflux Transporters

The objectives of this study were to investigate raltegravir transport across several blood-tissue barrier models and the potential interactions with drug efflux transporters. Raltegravir uptake, accumulation, and permeability were evaluated in vitro in (i) P-glycoprotein (P-gp), breast cancer resis...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Hoque, M. Tozammel, Kis, Olena, De Rosa, María F., Bendayan, Reina
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394805/
https://ncbi.nlm.nih.gov/pubmed/25691630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04594-14
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