Role of mitochondria in diabetic peripheral neuropathy: Influencing the NAD(+)-dependent SIRT1–PGC-1α–TFAM pathway

Survival of human peripheral nervous system neurons and associated distal axons is highly dependent on energy. Diabetes invokes a maladaptation in glucose and lipid energy metabolism in adult sensory neurons, axons and Schwann cells. Mitochondrial (Mt) dysfunction has been implicated as an etiologic...

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發表在:Int Rev Neurobiol
Main Authors: Chandrasekaran, Krish, Anjaneyulu, Muragundla, Choi, Joungil, Kumar, Pranith, Salimian, Mohammad, Ho, Cheng-Ying, Russell, James W.
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590704/
https://ncbi.nlm.nih.gov/pubmed/31208524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.irn.2019.04.002
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