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Role of mitochondria in diabetic peripheral neuropathy: Influencing the NAD(+)-dependent SIRT1–PGC-1α–TFAM pathway
Survival of human peripheral nervous system neurons and associated distal axons is highly dependent on energy. Diabetes invokes a maladaptation in glucose and lipid energy metabolism in adult sensory neurons, axons and Schwann cells. Mitochondrial (Mt) dysfunction has been implicated as an etiologic...
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| Publicado no: | Int Rev Neurobiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6590704/ https://ncbi.nlm.nih.gov/pubmed/31208524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.irn.2019.04.002 |
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