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Impact of cell culture media additives on IgG glycosylation produced in Chinese hamster ovary cells

Glycosylation is a key critical quality attribute for monoclonal antibodies and other recombinant proteins because of its impact on effector mechanisms and half‐life. In this study, a variety of compounds were evaluated for their ability to modulate glycosylation profiles of recombinant monoclonal a...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Ehret, Janike, Zimmermann, Martina, Eichhorn, Thomas, Zimmer, Aline
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590254/
https://ncbi.nlm.nih.gov/pubmed/30552760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26904
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