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Impact of cell culture media additives on IgG glycosylation produced in Chinese hamster ovary cells
Glycosylation is a key critical quality attribute for monoclonal antibodies and other recombinant proteins because of its impact on effector mechanisms and half‐life. In this study, a variety of compounds were evaluated for their ability to modulate glycosylation profiles of recombinant monoclonal a...
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| Published in: | Biotechnol Bioeng |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6590254/ https://ncbi.nlm.nih.gov/pubmed/30552760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26904 |
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