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Impact of Acetylated and Non-Acetylated Fucose Analogues on IgG Glycosylation
The biological activity of therapeutic antibodies is highly influenced by their glycosylation profile. A valuable method for increasing the cytotoxic efficacy of antibodies, which are used, for example, in cancer treatment, is the reduction of core fucosylation, as this enhances the elimination of t...
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| Pubblicato in: | Antibodies (Basel) |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6640710/ https://ncbi.nlm.nih.gov/pubmed/31544815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib8010009 |
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