Loops Govern SH2 Domain Specificity by Controlling Access to Binding Pockets

Cellular functions require specific protein-protein interactions that are often mediated by modular domains that use binding pockets to engage particular sequence motifs in their partners. Yet, how different members of a domain family select for distinct sequence motifs is not fully understood. The...

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Detaylı Bibliyografya
Yayımlandı:Sci Signal
Asıl Yazarlar: Kaneko, Tomonori, Huang, Haiming, Zhao, Bing, Li, Lei, Liu, Huadong, Voss, Courtney K., Wu, Chenggang, Schiller, Martin R., Li, Shawn Shun-Cheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590088/
https://ncbi.nlm.nih.gov/pubmed/20442417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000796
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