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Loops Govern SH2 Domain Specificity by Controlling Access to Binding Pockets
Cellular functions require specific protein-protein interactions that are often mediated by modular domains that use binding pockets to engage particular sequence motifs in their partners. Yet, how different members of a domain family select for distinct sequence motifs is not fully understood. The...
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| 出版年: | Sci Signal |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6590088/ https://ncbi.nlm.nih.gov/pubmed/20442417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000796 |
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