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Chemical Consequences of the Mechanical Bond: A Tandem Active Template‐Rearrangement Reaction

We report the unexpected discovery of a tandem active template CuAAC‐rearrangement process, in which N(2) is extruded on the way to the 1,2,3‐triazole product to give instead acrylamide rotaxanes. Mechanistic investigations suggest this process is dictated by the mechanical bond, which stabilizes th...

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Détails bibliographiques
Publié dans:Angew Chem Int Ed Engl
Auteurs principaux: Modicom, Florian, Jamieson, Ellen M. G., Rochette, Elise, Goldup, Stephen M.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589916/
https://ncbi.nlm.nih.gov/pubmed/30600892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201813950
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