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Chemical Consequences of the Mechanical Bond: A Tandem Active Template‐Rearrangement Reaction

We report the unexpected discovery of a tandem active template CuAAC‐rearrangement process, in which N(2) is extruded on the way to the 1,2,3‐triazole product to give instead acrylamide rotaxanes. Mechanistic investigations suggest this process is dictated by the mechanical bond, which stabilizes th...

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Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Modicom, Florian, Jamieson, Ellen M. G., Rochette, Elise, Goldup, Stephen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589916/
https://ncbi.nlm.nih.gov/pubmed/30600892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201813950
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